PLEKHM2 and SLC39A1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		PLEKHM2	SLC39A1
Description		pleckstrin homology and RUN domain containing M2	solute carrier family 39 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Membrane	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Kinesin Binding	Signaling Receptor Binding Zinc Ion Transmembrane Transporter Activity Protein Binding Inorganic Cation Transmembrane Transporter Activity
	Biological Process	Golgi Organization Lysosome Localization Regulation Of Protein Localization Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Membrane Tubulation	In Utero Embryonic Development Cation Transport Embryonic Cranial Skeleton Morphogenesis Limb Development Zinc Ion Transmembrane Transport
Pathways			Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Estimated glomerular filtration rate ( 31015462)	Age at first birth ( 27798627) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Lentiform nucleus volume ( 22903471) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: KLC1 SLC39A1	16 interacting genes: CERS2 COMT CXCL16 CXCL9 CYB561 HTR2C HTR4 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2 TRARG1 YIPF6
Entrez ID		23207	27173
HPRD ID		11440	11984
Ensembl ID		ENSG00000116786	ENSG00000143570
Uniprot IDs		Q8IWE5	A0A0A0MTL8 Q9NY26
PDB IDs		3CXB 3HW2 3ZFW
Enriched GO Terms of Interacting Partners?
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