TTLL12 and EEF1A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TTLL12	EEF1A2
Description		tubulin tyrosine ligase like 12	eukaryotic translation elongation factor 1 alpha 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Spindle Midbody	Nucleus Cytoplasm Eukaryotic Translation Elongation Factor 1 Complex Neuronal Cell Body Synapse Cytoplasmic Side Of Lysosomal Membrane
	Molecular Function	Tubulin-tyrosine Ligase Activity Protein Binding ATP Binding Tubulin Binding Histone-lysine N-methyltransferase Activity H4K20me3 Modified Histone Binding	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Translation Factor Activity, RNA Binding Protein Kinase Binding
	Biological Process	Cellular Protein Modification Process Regulation Of Mitotic Cell Cycle Innate Immune Response Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Histone H4-K20 Methylation	Translation Translational Elongation Response To Inorganic Substance Positive Regulation Of Apoptotic Process Response To Electrical Stimulus Positive Regulation Of Lipid Kinase Activity Regulation Of Chaperone-mediated Autophagy
Pathways		Carboxyterminal post-translational modifications of tubulin	Eukaryotic Translation Elongation
Drugs
Diseases
GWAS		Molar-incisor hypomineralization ( 23918034) Monocyte count ( 32888494 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Prostate cancer ( 23535732) Serum metabolite levels ( 33031748)
Interacting Genes		7 interacting genes: CSNK2A2 DNAJB1 EEF1A1 EEF1A2 FAM222B PRR35 SUMO2	11 interacting genes: ABTB1 CHRM4 ERG MAPK6 SMN1 STK11 SUMO2 TPT1 TSPY1 TTLL12 UBE3A
Entrez ID		23170	1917
HPRD ID		13782	04265
Ensembl ID		ENSG00000100304	ENSG00000101210
Uniprot IDs		A0A024R4U3 Q14166	Q05639
PDB IDs			3C5J
Enriched GO Terms of Interacting Partners?
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