TACC2 and HMG20B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TACC2	HMG20B
Description		transforming acidic coiled-coil containing protein 2	high mobility group 20B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane	Nucleus Nucleoplasm Chromosome Nuclear Body
	Molecular Function	Nuclear Receptor Binding	DNA Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development	Chromatin Organization Cell Cycle Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation
Pathways			HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia (time to first treatment) ( 33510140) Hepcidin/ferritin ratio ( 27846281) Metabolite risk score for predicting weight gain ( 31560688) Myopia (pathological) ( 23049088) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Obesity-related traits ( 23251661) Opioid dependence ( 31250797) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Total body bone mineral density ( 29304378)
Interacting Genes		18 interacting genes: AURKC BORCS6 CLK2 CLVS2 CREBBP EP300 FMR1 FXR1 GRAMD4 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCA2 SMARCB1 TGM1 YEATS4	29 interacting genes: APP BRCA2 C14orf119 CCDC102B CCDC136 CCDC85B E2F6 ERP29 FBXO7 HMG20A HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 NUTF2 PHF21A PIAS2 PPP1R13B SNAPC5 SYCE1 TACC2 TFIP11 TRAF1 TUBB4A USHBP1 VIM WAC
Entrez ID		10579	10362
HPRD ID		05600	05703
Ensembl ID		ENSG00000138162	ENSG00000064961
Uniprot IDs		B2RWP4 B7ZMJ9 D6RAA5 O95359 Q4VXL4 Q4VXL8	Q9P0W2
PDB IDs
Enriched GO Terms of Interacting Partners?
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