FNBP1 and SNX2

Number of citations of the paper that reports this interaction (PubMedID 11438682)
21

Data Source:
HPRD (two hybrid, in vivo)

		FNBP1	SNX2
Description		formin binding protein 1	sorting nexin 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Cell Cortex Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Cytoplasm Lysosome Endosome Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Protein-containing Complex
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Endocytosis Signal Transduction	Intracellular Protein Transport Endocytosis Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Lamellipodium Morphogenesis
Pathways		Clathrin-mediated endocytosis CDC42 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RND2 GTPase cycle	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) LDL peak particle diameter (total fat intake interaction) ( 26112879) Pediatric autoimmune diseases ( 26301688) Physiological dysregulation (Mahalanobis distance) ( 32235003)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308) Plateletcrit ( 32888494) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		13 interacting genes: AGTR1 AKAP9 ARHGAP17 CBL CDC42 DNM1 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL	28 interacting genes: ACVR1B ACVR2B ARL6IP1 C1orf122 CENPQ CSNK2B DUSP10 EGFR FNBP1 INSR LAMC1 LEPR MET MTIF3 NFYC PAK6 PDGFRA PDGFRB PLIN3 PNKP SNX1 SNX32 SNX4 SNX5 SNX6 TMEM239 YIF1A ZNF202
Entrez ID		23048	6643
HPRD ID		10446	09332
Ensembl ID		ENSG00000187239	ENSG00000205302
Uniprot IDs		B7ZL13 B7ZL14 Q96RU3	O60749
PDB IDs		2EFL
Enriched GO Terms of Interacting Partners?
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