FNBP1 and PDE6G

Number of citations of the paper that reports this interaction (PubMedID 14502124)
3

Data Source:
HPRD (two hybrid, in vitro)

		FNBP1	PDE6G
Description		formin binding protein 1	phosphodiesterase 6G
Image
GO Annotations	Cellular Component	Lysosome Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Cell Cortex Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	Enzyme Inhibitor Activity Protein Binding Spectrin Binding CGMP Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Endocytosis Signal Transduction	Visual Perception Negative Regulation Of Catalytic Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Stimulus
Pathways		Clathrin-mediated endocytosis CDC42 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RND2 GTPase cycle	Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Ca2+ pathway Ca2+ pathway
Drugs			Sildenafil Vardenafil 3-isobutyl-1-methyl-7H-xanthine
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) LDL peak particle diameter (total fat intake interaction) ( 26112879) Pediatric autoimmune diseases ( 26301688) Physiological dysregulation (Mahalanobis distance) ( 32235003)	Blond vs. brown/black hair color ( 30531825) High myopia ( 31816047) Refractive error ( 32231278)
Interacting Genes		13 interacting genes: AGTR1 AKAP9 ARHGAP17 CBL CDC42 DNM1 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL	12 interacting genes: BHLHE40 DNM2 FNBP1 GNAO1 GRB2 GRK2 L3MBTL3 MAPK3 PRKAB2 SLC27A2 SRC TRIP10
Entrez ID		23048	5148
HPRD ID		10446	08914
Ensembl ID		ENSG00000187239	ENSG00000185527
Uniprot IDs		B7ZL13 B7ZL14 Q96RU3	P18545
PDB IDs		2EFL	3JWR
Enriched GO Terms of Interacting Partners?
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