Description |
FES proto-oncogene, tyrosine kinase |
heat shock protein family A (Hsp70) member 4 |
Image |
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No pdb structure |
GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Birth weight ( 31043758 27680694)
- Blood pressure ( 21909110)
- Brain morphology (MOSTest) ( 32665545)
- Caffeine consumption from coffee ( 33287642)
- Coffee consumption ( 31046077)
- Coronary artery disease ( 32469254 29212778 30104761 26343387 33020668)
- Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
- Daytime sleep phenotypes ( 27126917)
- Diastolic blood pressure ( 27841878 21909115 28739976 27618452)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Hypertension ( 31879980 21909115)
- Ischemic stroke ( 29531354)
- Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
- Medication use (agents acting on the renin-angiotensin system) ( 31015401)
- Medication use (beta blocking agents) ( 31015401)
- Medication use (calcium channel blockers) ( 31015401)
- Medication use (diuretics) ( 31015401)
- Myocardial infarction ( 33532862 26343387)
- Number of sexual partners ( 30643258)
- Offspring birth weight ( 31043758)
- Parental lifespan ( 30642433)
- Pulse pressure ( 27841878 30578418)
- Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
- Schizophrenia ( 25056061 29483656 30285260)
- Stroke ( 29531354)
- Systolic blood pressure ( 26390057 28135244 27841878 21909115 28739976 27618452 30578418)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
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- Body shape index ( 34021172)
- Breast cancer ( 29059683)
- Chronic obstructive pulmonary disease ( 30804561)
- Diastolic blood pressure ( 30224653)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- Eyebrow thickness ( 26926045)
- HDL cholesterol levels ( 32203549)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Heel bone mineral density ( 30598549)
- High density lipoprotein cholesterol levels ( 31928498)
- High light scatter reticulocyte count ( 32888494)
- High light scatter reticulocyte percentage of red cells ( 32888494)
- Liver enzyme levels (alkaline phosphatase) ( 33972514)
- Mean reticulocyte volume ( 32888494)
- Mean spheric corpuscular volume ( 32888494)
- Metabolite levels ( 23823483)
- Reticulocyte count ( 32888494)
- Reticulocyte fraction of red cells ( 32888494 27863252)
- Triglyceride levels ( 32203549 31928498 30698716)
- Triglyceride levels in current drinkers ( 30698716)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Waist circumference adjusted for body mass index ( 34021172)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172)
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Interacting Genes |
50 interacting genes:
ALDH1B1
APP
AR
BCAR1
BCR
BLM
CBX5
CSF2RB
DOK1
DPYSL5
EGFR
ERBB2
ERBB3
ERBB4
FKBP4
FKBP5
FURIN
GAB1
HSH2D
HSPA4
IL4R
IRS1
IRS2
JAK1
JAK2
JAK3
KIT
MAN2A2
MDFI
MET
NEDD4
NLGN4X
PDE4DIP
PEX11A
PIK3R1
PLXNA1
POT1
PPID
PTGES3
RASA1
RASA3
SMURF1
STARD5
STAT3
TERF1
TRIM28
VANGL1
ZNF117
ZNF746
ZNF775
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69 interacting genes:
ABCC2
AGTRAP
AIMP2
APPBP2
BAG1
BAG2
BRMS1
CALM1
CD40
CDC73
CDKN2A
CSNK1A1
CSNK2A1
DDIT4
DNAJB2
DUSP1
EGFR
ESR1
FANCC
FES
FKBP4
GATA1
GRPEL2
GSK3B
GZMA
HAP1
HDAC3
HNRNPD
HSPB1
HSPBP1
IKBKG
KPNA2
KRT18
MUC1
NAA10
NEDD8
NFKB1
NR3C2
OLR1
PA2G4
PHLDA1
POU6F2
PPP1CA
PRKACA
PRKCB
PRKCD
PRKCG
PRSS23
PSMD10
PTEN
RAF1
RAP1A
REL
RELA
SENP8
SGTA
SIRPA
SMAD3
ST13
STUB1
SUGT1
TERT
TOMM40
TRAF6
TRIM32
TTC1
UBE2L3
UBE2M
UBE3A
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Entrez ID |
2242 |
3308 |
HPRD ID |
01814 |
09025 |
Ensembl ID |
ENSG00000182511
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ENSG00000170606
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Uniprot IDs |
A0A024RC92
P07332
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P34932
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PDB IDs |
1WQU
2DCR
3BKB
3CBL
3CD3
4DYL
4E93
6JMF
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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