PPIH and N4BP2L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PPIH	N4BP2L2
Description		peptidylprolyl isomerase H	NEDD4 binding protein 2 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP	Nucleus Transcription Repressor Complex Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding	Molecular_function Transcription Corepressor Activity Protein Binding Enzyme Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Positive Regulation Of Viral Genome Replication Protein-containing Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Development Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		mRNA Splicing - Major Pathway
Drugs		Proline
Diseases
GWAS			Adult body size ( 32376654) Breast cancer ( 23535729) Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Logical memory (delayed recall) ( 29274321) Myocardial infarction ( 33532862)
Interacting Genes		15 interacting genes: BAG2 BPIFA1 DOK3 IPO13 KDM4A LNX1 LNX2 N4BP2L2 NIF3L1 PRPF18 PRPF31 PRPF4 SNU13 UBQLN2 XIAP	7 interacting genes: EXOSC8 HOXA1 LMO2 NAA38 PPIA PPIH PPIL1
Entrez ID		10465	10443
HPRD ID		12084	15119
Ensembl ID		ENSG00000171960	ENSG00000244754
Uniprot IDs		O43447 Q6FH36	A0A024RDV2 B4DPY1 Q92802 Q9Y3H6
PDB IDs		1MZW 1QOI 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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