EPHB3 and RNF186

Number of citations of the paper that reports this interaction (PubMedID 33280498)
2

Data Source:
BioGRID (enzymatic study)

		EPHB3	RNF186
Description		EPH receptor B3	ring finger protein 186
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Dendrite Neuron Projection Receptor Complex	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding Axon Guidance Receptor Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Angiogenesis Urogenital System Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Axonal Fasciculation Cell Migration Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Corpus Callosum Development Regulation Of Cell-cell Adhesion Retinal Ganglion Cell Axon Guidance Positive Regulation Of Kinase Activity Substrate Adhesion-dependent Cell Spreading Regulation Of GTPase Activity Protein Autophosphorylation Ephrin Receptor Signaling Pathway Thymus Development Digestive Tract Morphogenesis Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Roof Of Mouth Development Dendritic Spine Development Dendritic Spine Morphogenesis	Protein K29-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Protein K63-linked Ubiquitination Protein Localization To Mitochondrion
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS		Facial morphology traits (63 three-dimensional facial segments) ( 29459680) Nicotine dependence symptom count ( 25555482) Nose size ( 27182965) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908 20228799 19122664 23511034)
Interacting Genes		14 interacting genes: AFDN CRK EFNB3 ERBB2 FBXO7 FYN GBE1 HPCAL1 HSF2BP LNX1 NFRKB RASA1 RNF186 RYK	8 interacting genes: EPHB2 EPHB3 HIVEP1 PBX3 SCAND1 SESN2 UBE2D2 UBE2H
Entrez ID		2049	54546
HPRD ID		03502	07885
Ensembl ID		ENSG00000182580	ENSG00000178828
Uniprot IDs		P54753	Q9NXI6
PDB IDs		3P1I 3ZFY 5L6O 5L6P
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?