EPHB3

Description		EPH receptor B3
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GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Dendrite Neuron Projection Receptor Complex
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding Axon Guidance Receptor Activity
	Biological Process	Angiogenesis Urogenital System Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Axonal Fasciculation Cell Migration Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Corpus Callosum Development Regulation Of Cell-cell Adhesion Retinal Ganglion Cell Axon Guidance Positive Regulation Of Kinase Activity Substrate Adhesion-dependent Cell Spreading Regulation Of GTPase Activity Protein Autophosphorylation Ephrin Receptor Signaling Pathway Thymus Development Digestive Tract Morphogenesis Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Roof Of Mouth Development Dendritic Spine Development Dendritic Spine Morphogenesis
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS		Facial morphology traits (63 three-dimensional facial segments) ( 29459680) Nicotine dependence symptom count ( 25555482) Nose size ( 27182965) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes		14 interacting genes: AFDN CRK EFNB3 ERBB2 FBXO7 FYN GBE1 HPCAL1 HSF2BP LNX1 NFRKB RASA1 RNF186 RYK
Entrez ID		2049
HPRD ID		03502
Ensembl ID		ENSG00000182580
Uniprot IDs		P54753
PDB IDs		3P1I 3ZFY 5L6O 5L6P
Enriched GO Terms of Interacting Partners?
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