EEF1G and RECQL5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		EEF1G	RECQL5
Description		eukaryotic translation elongation factor 1 gamma	RecQ like helicase 5
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol RNA Polymerase II, Holoenzyme
	Molecular Function	Translation Elongation Factor Activity Protein Binding Cadherin Binding	RNA Polymerase II Complex Binding Nucleic Acid Binding DNA Helicase Activity ATP Binding Four-way Junction Helicase Activity ATP Hydrolysis Activity 3'-5' DNA Helicase Activity
	Biological Process	Translational Elongation Glutathione Metabolic Process Response To Virus	Mitotic Cell Cycle Double-strand Break Repair Via Homologous Recombination DNA Metabolic Process DNA Replication DNA Unwinding Involved In DNA Replication DNA Repair DNA Recombination DNA Duplex Unwinding Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Cell Division Chromosome Separation Cellular Response To Xenobiotic Stimulus Cellular Response To Camptothecin Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways		Eukaryotic Translation Elongation Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Deep white matter hyperintensities ( 32517579) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		97 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DLG4 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FADS1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MBD1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 OGT PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	21 interacting genes: ADCY10P1 ALDH7A1 BNIPL CREB1 CUX1 DDX42 EEF1G ITGB3BP MAPK8IP1 MRE11 MTSS1 MUS81 NBN PCNA PLK1 RAD50 RAD51 STAMBP TIMP1 TOP3A TOP3B
Entrez ID		1937	9400
HPRD ID		11745	04806
Ensembl ID		ENSG00000254772	ENSG00000108469
Uniprot IDs		P26641 Q53YD7	A0A024R8M9 A0A024R8S8 B3KQK2 O94762 Q8WYH5
PDB IDs		1PBU 5DQS 5JPO	4BK0 5LB3 5LB5 5LB8 5LBA
Enriched GO Terms of Interacting Partners?
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