DYNC1H1 and COX20

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DYNC1H1	COX20
Description		dynein cytoplasmic 1 heavy chain 1	cytochrome c oxidase assembly factor COX20
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Cytoplasmic Microtubule Cell Cortex Membrane Filopodium Dynein Complex Azurophil Granule Lumen Extracellular Exosome Axon Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Protein Binding ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Microtubule-based Movement Mitotic Spindle Organization Nuclear Migration Retrograde Axonal Transport Cytoplasmic Microtubule Organization Positive Regulation Of Intracellular Transport P-body Assembly Stress Granule Assembly Establishment Of Spindle Localization Cell Division Regulation Of Mitotic Spindle Organization Minus-end-directed Vesicle Transport Along Microtubule Regulation Of Metaphase Plate Congression Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of Spindle Assembly	Mitochondrial Cytochrome C Oxidase Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase AURKA Activation by TPX2 HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
Interacting Genes		29 interacting genes: ASB7 ATP2B3 BRCA1 COX20 DISC1 DUX4 DYNLL1 ECSIT EGFR KATNA1 KATNB1 LINC01554 LMO4 MRE11 MTNR1B NDEL1 PAFAH1B1 PPP2R5C PRKCD PSMB9 RHBDD2 SMAD2 SORBS2 SUMO2 TENT5A TNIK YWHAG YWHAQ ZBTB42	22 interacting genes: AQP6 C1orf56 CHIA CREB3L1 DYNC1H1 ERGIC3 FCER1G FUNDC2 GET1 GJA8 GOLT1A JAGN1 MAOB NCBP2AS2 PGRMC2 SLC10A1 SLC10A6 TCEA2 TEX44 TMEM31 TMEM35A TMX2
Entrez ID		1778	116228
HPRD ID		02524	13307
Ensembl ID		ENSG00000197102	ENSG00000203667
Uniprot IDs		Q14204	B3KM21 Q5RI15
PDB IDs		2BOR 2BOT 5NUG 5OWO 6F1T 6F1U 6F1V 6F1Y 6F38 6F3A
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?