DNAH5 and CDH6

		DNAH5	CDH6
Description		dynein axonemal heavy chain 5	cadherin 6
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Microtubule Axoneme Dynein Complex Motile Cilium Outer Dynein Arm 9+2 Motile Cilium	Nucleoplasm Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex Cell Junction
	Molecular Function	ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Calcium Ion Binding Cadherin Binding
	Biological Process	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Microtubule-based Movement Determination Of Left/right Symmetry Heart Development Lateral Ventricle Development Flagellated Sperm Motility Outer Dynein Arm Assembly Establishment Of Localization In Cell Cilium Assembly	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Notch Signaling Pathway Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways			Adherens junctions interactions
Drugs
Diseases
GWAS		Antidepressant treatment resistance (number of drugs prescribed) ( 30700811) Coffee consumption ( 29367735) Cognitive function in longevity ( 33607172) Corneal astigmatism ( 23322567) Emphysema imaging phenotypes ( 26030696) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) IgE grass sensitization ( 22036096) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Subclinical atherosclerosis traits (other) ( 17903303) Thyroid volume in Hashimotoâ€™s thyroiditis ( 32019955) Toxicity response to radiotherapy in prostate cancer (decreased urine stream) (time to event) ( 27515689) Visceral fat ( 22589738)	Adventurousness ( 30643258) Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Cocaine dependence ( 31212010) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Emphysema-related traits ( 20709820) Gamma glutamyl transferase levels ( 29403010 33339817) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549 28869591) Late-onset myasthenia gravis ( 26562150) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 22001757) Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Resting heart rate ( 27798624) Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524) Sleep (1/3-day periodicity) ( 33075057) Smoking status (ever vs never smokers) ( 30643258) Sweet taste preference ( 32572145) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		14 interacting genes: CDH6 CKB CTNND2 DAP LARGE1 MARCHF6 MICAL1 MTDH MVP MYO10 RAN RBFOX2 TLE1 TRIO	6 interacting genes: CDH10 CDH18 CDH19 CDH7 CDH9 DNAH5
Entrez ID		1767	1004
HPRD ID		04514	04305
Ensembl ID		ENSG00000039139	ENSG00000113361
Uniprot IDs		Q8TE73	P55285
PDB IDs			5VEB
Enriched GO Terms of Interacting Partners?
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