FAM9A and MLLT3

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		FAM9A	MLLT3
Description		family with sequence similarity 9 member A	MLLT3 super elongation complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleolus	Nucleus Nucleoplasm Chromosome Cytosol Transcription Elongation Factor Complex Extracellular Exosome
	Molecular Function	Protein Binding	DNA Binding Chromatin Binding Protein Binding Histone Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Segment Specification Anterior/posterior Pattern Specification Gene Expression Positive Regulation Of Transcription, DNA-templated Hematopoietic Stem Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Chromatin Organization Regulation Of Stem Cell Division Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways			Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Creatinine levels ( 29403010) Estradiol levels ( 34255042) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965)	Atrial fibrillation ( 29892015) Dietary fat liking ( 32516399) Estimated glomerular filtration rate ( 31152163) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Platelet distribution width ( 32888494) Response to montelukast in asthma (change in FEV1) ( 26083242) Systolic blood pressure ( 30578418)
Interacting Genes		39 interacting genes: ARPC3 CTNNA3 ESRRA ESRRG FAM9B H2BC15 HOMER1 INTS12 KDM1A KMT5A LCE1E MCRS1 MLLT3 NAB2 NXF1 PHC1 PICK1 PRMT1 PRR20A PRR20B PRR20C PRR20D PRR20E RNF151 RNF4 RUNX1T1 SDCBP STAC3 THAP1 TRAF2 TRAF5 TRIM41 TRIM54 TXLNA VCX ZBTB6 ZDHHC17 ZFP91 ZNF775	20 interacting genes: AFF1 ALKBH4 APP APPBP2 BCOR CBX8 CDK6 COL6A1 EEF1A1 FAM9A H3C1 LRIF1 LRRK2 MCM6 MIIP PTN RBM48 SGK1 VAX1 ZNF572
Entrez ID		171482	4300
HPRD ID		06506	01163
Ensembl ID		ENSG00000183304	ENSG00000171843
Uniprot IDs		Q8IZU1	A0A0S2Z448 P42568
PDB IDs			2LM0 2MV7 2N4Q 2NDF 2NDG 4TMP 5HJB 5HJD 5YYF 6B7G 6L5Z 6LS6 6MIL 6MIM
Enriched GO Terms of Interacting Partners?
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