FAM9A and ARPC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM9A	ARPC3
Description		family with sequence similarity 9 member A	actin related protein 2/3 complex subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleolus	Nucleus Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Filamentous Actin Site Of Double-strand Break Growth Cone Leading Edge Extracellular Exosome
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Arp2/3 Complex-mediated Actin Nucleation Actin Polymerization-dependent Cell Motility Cellular Response To Nerve Growth Factor Stimulus
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Age at voice drop ( 27182965) Creatinine levels ( 29403010) Estradiol levels ( 34255042) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965)	Automobile speeding propensity ( 30643258) Bipolar disorder ( 31043756) Femoral neck bone mineral density ( 30172743)
Interacting Genes		39 interacting genes: ARPC3 CTNNA3 ESRRA ESRRG FAM9B H2BC15 HOMER1 INTS12 KDM1A KMT5A LCE1E MCRS1 MLLT3 NAB2 NXF1 PHC1 PICK1 PRMT1 PRR20A PRR20B PRR20C PRR20D PRR20E RNF151 RNF4 RUNX1T1 SDCBP STAC3 THAP1 TRAF2 TRAF5 TRIM41 TRIM54 TXLNA VCX ZBTB6 ZDHHC17 ZFP91 ZNF775	32 interacting genes: ACTR3 ARAP1 ARPC4 BAG6 CCR10 CDKN2B CETP DUSP29 EFTUD2 FAM9A GOLGA2 HOXA3 LATS1 LGALS4 LTA4H MAPK6 NRIP1 OTUD5 POU2F1 PRMT1 RBBP8NL RETREG3 RPS4X SRPK2 SYBU TARS3 THNSL2 WAS WASF2 WASHC4 WASL ZNF576
Entrez ID		171482	10094
HPRD ID		06506	09175
Ensembl ID		ENSG00000183304	ENSG00000111229
Uniprot IDs		Q8IZU1	O15145
PDB IDs			6UHC 6YW6 6YW7
Enriched GO Terms of Interacting Partners?
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