AP1B1 and CDC42EP1

		AP1B1	CDC42EP1
Description		adaptor related protein complex 1 subunit beta 1	CDC42 effector protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Endomembrane System
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Kidney Development Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cell-cell Adhesion
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Carotid atherosclerosis in HIV infection ( 20009918) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Pancreatic cancer ( 25086665) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		51 interacting genes: - AGR3 AP1G1 AP1G2 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CDC42EP1 CLTC CREBBP CRYBB1 CYTH4 FARS2 FBXO7 FMNL2 FNDC11 GPANK1 GTF2I KIF13A LDLRAP1 ME1 MLH1 MSGN1 MTNR1B MYG1 NECAP1 NTRK2 NUP54 PARD3 PHF5A PIP5K1C POM121 PRKDC PSME1 PSORS1C2 RNF39 SHBG SLC2A8 SMAD2 TBC1D22B TEX33 TSGA10IP U2AF1	15 interacting genes: AP1B1 ARMC7 CDC42 DEF6 FHL3 KRTAP4-12 MAPKAP1 MDFI OGT PLSCR1 PRKAA2 RBPMS RHOJ RHOQ SAT1
Entrez ID		162	11135
HPRD ID		02541	07303
Ensembl ID		ENSG00000100280	ENSG00000128283
Uniprot IDs		Q10567	Q00587
PDB IDs		4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF
Enriched GO Terms of Interacting Partners?
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