AP1B1 and -

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AP1B1	-
Description		adaptor related protein complex 1 subunit beta 1	U2 small nuclear RNA auxiliary factor 1 like 5
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Nucleoplasm Spliceosomal Complex Nuclear Speck U2AF Complex
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	Kidney Development Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport	MRNA Splicing, Via Spliceosome
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Carotid atherosclerosis in HIV infection ( 20009918) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Pancreatic cancer ( 25086665) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		51 interacting genes: - AGR3 AP1G1 AP1G2 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CDC42EP1 CLTC CREBBP CRYBB1 CYTH4 FARS2 FBXO7 FMNL2 FNDC11 GPANK1 GTF2I KIF13A LDLRAP1 ME1 MLH1 MSGN1 MTNR1B MYG1 NECAP1 NTRK2 NUP54 PARD3 PHF5A PIP5K1C POM121 PRKDC PSME1 PSORS1C2 RNF39 SHBG SLC2A8 SMAD2 TBC1D22B TEX33 TSGA10IP U2AF1	15 interacting genes: AP1B1 AP2B1 CARNMT1 EFHC2 HNRNPK KRT1 KRT75 MEOX2 MLH1 SNRNP35 SRRM4 SRSF3 TRA2B U2AF2 ZNF417
Entrez ID		162	102724594
HPRD ID		02541
Ensembl ID		ENSG00000100280	ENSG00000275895
Uniprot IDs		Q10567	P0DN76 Q01081
PDB IDs		4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF	1JMT
Enriched GO Terms of Interacting Partners?
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