CFAP206 and APIP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CFAP206	APIP
Description		cilia and flagella associated protein 206	APAF1 interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Radial Spoke Axoneme Motile Cilium Ciliary Basal Body A Axonemal Microtubule	Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity
	Biological Process	Cilium Movement Regulation Of Cilium Beat Frequency Sperm Axoneme Assembly Axoneme Assembly Regulation Of Flagellated Sperm Motility	Apoptotic Process L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine Negative Regulation Of Apoptotic Process Protein Homotetramerization Pyroptosis Regulation Of ERK1 And ERK2 Cascade
Pathways			Formation of apoptosome Methionine salvage pathway Regulation of the apoptosome activity
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010 33339817) Lung disease severity in cystic fibrosis ( 26417704) Prostate-specific antigen levels ( 28139693) Systemic lupus erythematosus ( 19838195)
Interacting Genes		64 interacting genes: ADAMTSL4 ANKRD55 APIP ATPAF2 BANP BLZF1 C1orf94 C9orf153 CCDC33 CDX2 CEP57L1 CFP CPSF7 CRX CYSRT1 DISC1 EIF4ENIF1 GFAP GLYR1 GPRASP2 GSE1 HOMEZ IHO1 IKZF3 KIAA1328 KLHL3 KRT31 KRT34 KRT40 KRT75 KRT76 KRTAP13-1 KRTAP26-1 LZTS2 MAGED1 MDFI MEOX2 MIF4GD NME4 PIH1D2 PRDM16 PSMA1 PSMC5 REL RNF138 ROCK1 SAMD3 SAXO1 SORBS3 SOX30 TADA2B TASOR2 TCF12 TEKT1 TFIP11 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 VPS52 ZBTB32 ZNF511	19 interacting genes: APAF1 BAZ2B CFAP206 GORASP2 IMPDH2 LNX1 NIF3L1 NTAQ1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 TSC22D4 VIM VPS25 ZBTB25
Entrez ID		154313	51074
HPRD ID		12863	14725
Ensembl ID		ENSG00000272514	ENSG00000149089
Uniprot IDs		Q8IYR0 Q8N771	Q96GX9
PDB IDs			4M6R
Enriched GO Terms of Interacting Partners?
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