CLDN19 and SLAMF6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLDN19	SLAMF6
Description		claudin 19	SLAM family member 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Structural Molecule Activity Identical Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly	Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-17 Production T Cell Activation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity T-helper 17 Cell Lineage Commitment
Pathways		Tight junction interactions	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Graves' disease ( 23612905) Multiple sclerosis ( 24076602) Rheumatoid arthritis ( 32723749)
Interacting Genes		63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14	11 interacting genes: BRICD5 CLDN19 CXCL14 JAGN1 PTPN11 PTPN6 RABAC1 SH2D1A TMBIM6 TMPPE ZAP70
Entrez ID		149461	114836
HPRD ID		10834	05920
Ensembl ID		ENSG00000164007	ENSG00000162739
Uniprot IDs		Q8N6F1	B4E1U5 Q96DU3
PDB IDs			2IF7
Enriched GO Terms of Interacting Partners?
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