SLAMF6 and TMPPE

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLAMF6	TMPPE
Description		SLAM family member 6	transmembrane protein with metallophosphoesterase domain
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-17 Production T Cell Activation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity T-helper 17 Cell Lineage Commitment
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Graves' disease ( 23612905) Multiple sclerosis ( 24076602) Rheumatoid arthritis ( 32723749)	Asthma ( 31959851 31619474) Asthma (childhood onset) ( 31036433)
Interacting Genes		11 interacting genes: BRICD5 CLDN19 CXCL14 JAGN1 PTPN11 PTPN6 RABAC1 SH2D1A TMBIM6 TMPPE ZAP70	35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1
Entrez ID		114836	643853
HPRD ID		05920	18951
Ensembl ID		ENSG00000162739	ENSG00000188167
Uniprot IDs		B4E1U5 Q96DU3	Q6ZT21
PDB IDs		2IF7
Enriched GO Terms of Interacting Partners?
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