MIPOL1 and MCM7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MIPOL1	MCM7
Description		mirror-image polydactyly 1	minichromosome maintenance complex component 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Membrane MCM Complex CMG Complex
	Molecular Function	Protein Binding Identical Protein Binding	DNA Binding DNA Helicase Activity Single-stranded DNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Single-stranded DNA Helicase Activity
	Biological Process		Double-strand Break Repair Via Break-induced Replication DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication Cellular Response To DNA Damage Stimulus Cell Population Proliferation Response To Xenobiotic Stimulus Regulation Of Phosphorylation Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Xenobiotic Stimulus
Pathways			Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 29617998) Longitudinal alcohol consumption ( 26081443) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Red blood cell count ( 32888494) Tonsillectomy ( 27182965 28928442)	Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		75 interacting genes: ANKRD23 ARNT2 ATP5PO BEX2 BYSL C1orf109 C1orf35 C2CD6 CCDC120 CCDC146 CCDC33 CCT3 CDC37 CDK18 CKS1B DAXX DGCR6 EAF1 EIF4E2 ENKD1 EXOC8 FAM124B FAM161A FAM161B FAM90A1 FBF1 FMNL2 GADD45GIP1 GEM HAUS1 KDF1 KIF9 LAGE3 LENG1 MAGEA6 MBD3 MCM7 MFAP1 MOS MYLIP NEBL NTAQ1 PAX6 PBX4 PKN1 PPP1R13B PRDM16 PRPF31 RBM41 RCOR3 REL RIIAD1 RNF6 RPL10L RTP5 SCNM1 SHANK3 SMARCE1 SNAP91 SNTG2 SRPK2 SSX3 STMN3 TBC1D7 TCHP TSEN15 TSGA10IP TTC12 TXN2 UBE2I UBE2K USH1C UTP25 ZGPAT ZNF688	78 interacting genes: ABI2 AK8 APP ASB8 C8orf34 CCDC102B CCND1 CCNH CDC42 CDC45 CDC6 CDC7 CDK7 CDKN1B CEP68 CHEK1 COG6 CRLS1 DBF4 DNAAF6 DUX4 DYNC1I1 ELOC ESCO2 FHL2 GOLGA2 H3-4 HIF1A IKBKG IKZF3 INTS6 KIFC3 LINC01554 LNX2 MAGEA6 MBIP MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM8 MCMBP MEOX2 MIPOL1 MNAT1 NAB2 NFKBIA ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PLK1 PNMA1 RAD17 RB1 RBL1 RBL2 RBM8A RBPMS RINT1 RPA1 SMC1A SNTA1 SP2 SSX2IP TFIP11 TREX1 TRIM27 TRIM54 TRIM55 TRIM63 UBE3A UBQLN1 USHBP1
Entrez ID		145282	4176
HPRD ID		06029	01154
Ensembl ID		ENSG00000151338	ENSG00000166508
Uniprot IDs		A8K735 G5EA54 Q4G0U7 Q8TD10	A0A0S2Z4A5 C6EMX8 P33993
PDB IDs			6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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