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COL1A2 and SMARCD1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
COL1A2
SMARCD1
Description
collagen type I alpha 2 chain
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image
GO Annotations
Cellular Component
Extracellular Region
Collagen Type I Trimer
Extracellular Space
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Extracellular Exosome
Nucleus
Nucleoplasm
SWI/SNF Complex
Intracellular Membrane-bounded Organelle
NpBAF Complex
NBAF Complex
Molecular Function
Protease Binding
Extracellular Matrix Structural Constituent
Protein Binding
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Protein-macromolecule Adaptor Activity
Identical Protein Binding
SMAD Binding
Metal Ion Binding
Platelet-derived Growth Factor Binding
Chromatin Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
Signaling Receptor Binding
Protein Binding
Molecular Adaptor Activity
Biological Process
Skeletal System Development
Blood Vessel Development
Transforming Growth Factor Beta Receptor Signaling Pathway
Rho Protein Signal Transduction
Regulation Of Blood Pressure
Extracellular Matrix Organization
Collagen Fibril Organization
Bone Mineralization
Collagen Metabolic Process
Odontogenesis
Skin Morphogenesis
Protein Heterotrimerization
Cellular Response To Amino Acid Stimulus
Extracellular Matrix Assembly
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Chromatin-mediated Maintenance Of Transcription
Cellular Response To Fatty Acid
Pathways
GPVI-mediated activation cascade
Collagen degradation
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Assembly of collagen fibrils and other multimeric structures
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Integrin cell surface interactions
Anchoring fibril formation
Crosslinking of collagen fibrils
Syndecan interactions
Non-integrin membrane-ECM interactions
ECM proteoglycans
ECM proteoglycans
Scavenging by Class A Receptors
GP1b-IX-V activation signalling
Interleukin-4 and Interleukin-13 signaling
Platelet Adhesion to exposed collagen
Platelet Adhesion to exposed collagen
Platelet Aggregation (Plug Formation)
MET activates PTK2 signaling
Collagen chain trimerization
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS
Aging (
22773346
)
Heel bone mineral density (
30598549
)
Immune reponse to smallpox (secreted IL-12p40) (
22610502
)
Intelligence (
22449649
)
Low bone mineral density (hip) (
26235824
)
Low bone mineral density (spine) (
26235824
)
Mean forced vital capacity from 2 exams (
17903307
)
Post bronchodilator FEV1 (
26634245
)
PR interval in Tripanosoma cruzi seropositivity (
24324551
)
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Interacting Genes
31 interacting genes:
APP
BGN
CD36
CD44
CD93
COL5A3
DCN
EIF3F
FN1
ITGA2
ITGA2B
ITGB3
KCNIP4
LIG4
LUM
MESD
MMP9
MYOC
P4HB
PDGFA
PDGFB
SERPINB5
SGTA
SGTB
SHBG
SMARCD1
SPARC
TGFBI
UBQLN1
UBQLN2
VWF
157 interacting genes:
ABI1
ABI2
ABI3
ADAT2
ANKRD23
ANKRD49
ANKS1A
ANP32B
APOA5
AR
ARMC10
ARRDC3
BCAS2
BEND5
BEX3
BHLHB9
BLOC1S5
BRWD1
C19orf54
C1orf109
C4BPA
CALCOCO2
CCDC102B
CCDC197
CCDC33
CCDC85B
CDC5L
CDR2
CDSN
CDX2
CEACAM6
CHFR
CHN2
CLNK
COG6
COL1A2
CORO1A
CUEDC1
CYSRT1
DCTN2
DISC1
EGFL7
EIF4G1
ESR1
ESS2
FAM136A
FAM161A
FBXO7
FEZ1
FOS
FUS
GATA1
GCC1
GIGYF1
GINS3
GOLGA6L9
GRAMD4
HES6
HNRNPC
HOMEZ
HOXD3
HSF2BP
HSPB1
IGKC
IKBIP
IKZF3
INSC
IQCB1
JUN
KATNBL1
KDM1A
KEAP1
KIAA0753
KLF1
KMT5B
KRT15
KRT16
KRT18
KRT27
KRT31
KRT34
KRT37
KRT38
KRT75
LDB2
LDOC1
LZTS2
MAGEA2
MAGEA2B
MAGEA6
MED4
MKRN3
MTNR1B
MTUS2
NAB2
NECAB2
NELFA
NME1
NONO
NR1H4
NR3C1
NUCB2
NUDT16L1
NUTM1
OGT
PACSIN3
PAICS
PBX4
PCBD1
PGR
PICK1
PIH1D1
PKNOX2
PLAGL2
PPM1J
PRDX1
PRMT6
PSTPIP1
RIF1
RORB
RPS29
SCARA5
SCHIP1
SCNM1
SERTAD3
SHISA6
SMARCB1
SMUG1
SNF8
SPSB2
STH
STMN3
SYCE1L
TCP10L
THOC7
TLE5
TNIP2
TP53
TRIM27
TRIM54
TRIM72
USHBP1
USP54
VPS37B
WASHC1
WWP2
YJU2B
YWHAG
ZC2HC1C
ZMAT5
ZMYND12
ZNF417
ZNF438
ZNF511
ZNF629
ZNF655
ZNF69
Entrez ID
1278
6602
HPRD ID
00363
03438
Ensembl ID
ENSG00000164692
ENSG00000066117
Uniprot IDs
A0A0S2Z3H5
P08123
Q96GM5
PDB IDs
5CTD
5CTI
5CVA
6JEC
6LTH
6LTJ
Enriched GO Terms of Interacting Partners
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