GABPB2 and TSEN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GABPB2	TSEN2
Description		GA binding protein transcription factor subunit beta 2	tRNA splicing endonuclease subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	TRNA-intron Endonuclease Complex Nucleoplasm Nucleolus Centrosome Cytosol
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Identical Protein Binding	TRNA-intron Endonuclease Activity Nucleic Acid Binding Protein Binding Lyase Activity
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			tRNA processing in the nucleus
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971)	Body shape index ( 34021172) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Systemic lupus erythematosus ( 28714469) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: CRK GABPA GORASP2 KDM1A LONRF1 PLCG2 RYBP SNRPB2 TARS2 TSEN2 VAC14 ZDHHC17	8 interacting genes: CADPS CTAG2 GABPB2 NUP210 RANBP10 TAX1BP1 TEPSIN TSEN54
Entrez ID		126626	80746
HPRD ID		14536	10576
Ensembl ID		ENSG00000143458	ENSG00000154743
Uniprot IDs		Q5SZG2 Q8TAK5	A0A024R2G3 Q8NCE0
PDB IDs
Enriched GO Terms of Interacting Partners?
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