GABPB2 and GABPA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GABPB2	GABPA
Description		GA binding protein transcription factor subunit beta 2	GA binding protein transcription factor subunit alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Identical Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Formation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Cell Differentiation Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dopamine
Pathways			Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971)	Glaucoma (primary open-angle) ( 33627673) Gout (normal type) ( 32238385) Nicotine dependence symptom count ( 25555482)
Interacting Genes		12 interacting genes: CRK GABPA GORASP2 KDM1A LONRF1 PLCG2 RYBP SNRPB2 TARS2 TSEN2 VAC14 ZDHHC17	15 interacting genes: APP ATF1 CREBBP EP300 GABPB1 GABPB2 HCFC1 MED1 OGT PINX1 SP1 SP3 STK16 TMPRSS15 ZC2HC1B
Entrez ID		126626	2551
HPRD ID		14536	11793
Ensembl ID		ENSG00000143458	ENSG00000154727
Uniprot IDs		Q5SZG2 Q8TAK5	A8IE48 Q06546 Q8IYS3
PDB IDs
Enriched GO Terms of Interacting Partners?
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