HEXIM2 and CTIF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HEXIM2	CTIF
Description		HEXIM P-TEFb complex subunit 2	cap binding complex dependent translation initiation factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding	RNA Binding Protein Binding Translation Activator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Translational Initiation Positive Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)	Automobile speeding propensity ( 30643258) Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Iris heterochromicity ( 30895295) Large HDL particle concentration ( 29084231) Lumbar spine bone mineral density (integral) ( 27476799) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231) Red blood cell count ( 32888494 27863252) Response to carboplatin in ovarian cancer (MTT IC50) ( 27047539) Rheumatoid arthritis ( 30891314) White blood cell count ( 32888494)
Interacting Genes		49 interacting genes: ADAMTSL4 AHCYL1 AP2M1 CACNB2 CCDC33 CCNT1 CDK9 CFP CTIF DBF4B EGFL7 FAM161A GAS8 GATA1 HEXIM1 HOXA1 HSF2BP IHO1 KPNA3 KPRP KRTAP13-3 LNX1 MEOX2 PICK1 PIM1 PIN1 PRDM14 PSMA1 RNPS1 SAXO1 SDCBP SPRED1 SPRY1 SPRY2 TADA3 TCF12 TERF1 TERF2 TLE5 TNFAIP1 TRIM14 YPEL3 ZNF250 ZNF426 ZNF500 ZNF558 ZNF655 ZNF699 ZNF789	9 interacting genes: ATPAF2 ATXN7L2 DDX19A HEXIM2 HOOK3 MIF4GD RECK SPG21 TCF4
Entrez ID		124790	9811
HPRD ID		08129	11083
Ensembl ID		ENSG00000168517	ENSG00000134030
Uniprot IDs		Q96MH2	A0A024R259 O43310
PDB IDs
Enriched GO Terms of Interacting Partners?
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