HEXIM2 and SAXO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HEXIM2	SAXO1
Description		HEXIM P-TEFb complex subunit 2	stabilizer of axonemal microtubules 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Centriole Cytoskeleton Axonemal Microtubule Motile Cilium Ciliary Basal Body Sperm Flagellum
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding	Protein Binding Microtubule Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated	Cold Acclimation Cell Projection Organization Microtubule Anchoring Positive Regulation Of Cilium Assembly Protein Stabilization Cellular Response To Cold
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)	Cardiovascular event in colchicine-treated recent myocardial infarction (time to event) ( 33560138) Prudent dietary pattern ( 28644415)
Interacting Genes		49 interacting genes: ADAMTSL4 AHCYL1 AP2M1 CACNB2 CCDC33 CCNT1 CDK9 CFP CTIF DBF4B EGFL7 FAM161A GAS8 GATA1 HEXIM1 HOXA1 HSF2BP IHO1 KPNA3 KPRP KRTAP13-3 LNX1 MEOX2 PICK1 PIM1 PIN1 PRDM14 PSMA1 RNPS1 SAXO1 SDCBP SPRED1 SPRY1 SPRY2 TADA3 TCF12 TERF1 TERF2 TLE5 TNFAIP1 TRIM14 YPEL3 ZNF250 ZNF426 ZNF500 ZNF558 ZNF655 ZNF699 ZNF789	48 interacting genes: ACTN2 AKAP8L ARMC7 BAG4 BEGAIN C19orf54 CARD9 CDKN2D CFAP206 CHERP CPNE7 CRK CYSRT1 FAM124A FBXO17 FHL2 FHL3 FHL5 GLYCTK HEXIM2 HOMER3 HSF2BP IQUB KIR3DX1 KLHL40 LMO1 LMO2 MAPK9 MVP NEK6 NUDT22 OIP5 OSGIN1 PFDN5 PLEKHG4 PM20D2 POLR1C SMARCB1 SORBS3 STK16 TNK1 TRIB3 TRIP6 VPS28 WWOX ZMAT1 ZMYND12 ZMYND19
Entrez ID		124790	158297
HPRD ID		08129	16676
Ensembl ID		ENSG00000168517	ENSG00000155875
Uniprot IDs		Q96MH2	B3KQ57 F6S232 Q5VZT6 Q8IYX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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