CLNS1A and EIF4A2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		CLNS1A	EIF4A2
Description		chloride nucleotide-sensitive channel 1A	eukaryotic translation initiation factor 4A2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cytoskeleton Plasma Membrane Methylosome PICln-Sm Protein Complex	Cytosol Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding	RNA Binding RNA Helicase Activity Translation Initiation Factor Activity Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity
	Biological Process	Spliceosomal SnRNP Assembly Chloride Transport Cell Volume Homeostasis MRNA Cis Splicing, Via Spliceosome	Cytoplasmic Translational Initiation Regulation Of Translational Initiation Negative Regulation Of RNA-directed 5'-3' RNA Polymerase Activity Cellular Response To Leukemia Inhibitory Factor
Pathways		snRNP Assembly	ISG15 antiviral mechanism L13a-mediated translational silencing of Ceruloplasmin expression Deadenylation of mRNA Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Platelet distribution width ( 32888494) Tourette syndrome ( 30818990)
Interacting Genes		18 interacting genes: ACTB ALK CSNK2A1 EIF4A2 EPB41 EPB41L3 FRMD7 ITGA2B LSM10 LSM3 LSM6 PRMT5 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPG WDR77	23 interacting genes: BRCA1 CLNS1A DPPA4 ECT2 EIF4G1 EIF4G2 GOLGA2 HSPB2 IPO11 LINC01554 MCPH1 MDFI NEK2 PDCD4 PFDN1 PIH1D2 SLC16A9 SSX2IP SUMO2 TK1 TRIM36 TRIM39 ZNF620
Entrez ID		1207	1974
HPRD ID		03694	03062
Ensembl ID		ENSG00000074201	ENSG00000156976
Uniprot IDs		E9PJF4 E9PMI6 J3KN38 P54105	Q14240
PDB IDs		6V0O	3BOR
Enriched GO Terms of Interacting Partners?
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