EIF4A2 and SLC16A9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		EIF4A2	SLC16A9
Description		eukaryotic translation initiation factor 4A2	solute carrier family 16 member 9
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm	Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding RNA Helicase Activity Translation Initiation Factor Activity Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Symporter Activity
	Biological Process	Cytoplasmic Translational Initiation Regulation Of Translational Initiation Negative Regulation Of RNA-directed 5'-3' RNA Polymerase Activity Cellular Response To Leukemia Inhibitory Factor	Monocarboxylic Acid Transport Urate Metabolic Process Transmembrane Transport
Pathways		ISG15 antiviral mechanism L13a-mediated translational silencing of Ceruloplasmin expression Deadenylation of mRNA Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS			Acylcarnitine levels ( 26068415) Alopecia areata ( 25608926) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Gout ( 33832965 31578528) HDL cholesterol levels ( 32203549) Hemoglobin ( 32888494) Manganese levels ( 26025379) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Metabolic traits ( 21886157) Metabolite levels ( 23823483) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Platelet distribution width ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748 23093944) Serum metabolite ratios in chronic kidney disease ( 29545352) Serum uric acid levels ( 30993211) Systolic blood pressure (alcohol consumption interaction) ( 24376456) Total carotid plaque area (excess vs minimal atherosclerosis) ( 32811377) Triglyceride levels ( 32203549) Urate levels ( 31578528 23263486) Uric acid levels ( 19503597)
Interacting Genes		23 interacting genes: BRCA1 CLNS1A DPPA4 ECT2 EIF4G1 EIF4G2 GOLGA2 HSPB2 IPO11 LINC01554 MCPH1 MDFI NEK2 PDCD4 PFDN1 PIH1D2 SLC16A9 SSX2IP SUMO2 TK1 TRIM36 TRIM39 ZNF620	3 interacting genes: EIF4A2 KLC4 MRPL11
Entrez ID		1974	220963
HPRD ID		03062	15348
Ensembl ID		ENSG00000156976	ENSG00000165449
Uniprot IDs		Q14240	Q7RTY1
PDB IDs		3BOR
Enriched GO Terms of Interacting Partners?
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