NUDT3 and FXYD3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		NUDT3	FXYD3
Description		nudix hydrolase 3	FXYD domain containing ion transport regulator 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity	Chloride Channel Activity Sodium Channel Regulator Activity
	Biological Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process RNA Decapping Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process	Potassium Ion Transport Sodium Ion Transport Chloride Transport Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Synthesis of pyrophosphates in the cytosol	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29381148 20935630) Body shape index ( 34021172) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Fasting insulin ( 34059833) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 34021172) Myeloproliferative neoplasms ( 33057200) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1	64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3
Entrez ID		11165	5349
HPRD ID		14849	05410
Ensembl ID		ENSG00000272325	ENSG00000089356
Uniprot IDs		O95989	Q14802
PDB IDs		2FVV 2Q9P 6PCK 6PCL 6WO7 6WO8 6WO9 6WOA 6WOB 6WOC 6WOD 6WOE 6WOF 6WOG 6WOH 6WOI
Enriched GO Terms of Interacting Partners?
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