HHLA2 and UNC93B1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HHLA2	UNC93B1
Description		HERV-H LTR-associating 2	unc-93 homolog B1, TLR signaling regulator
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component External Side Of Plasma Membrane Integral Component Of Membrane	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome
	Molecular Function	Molecular_function Signaling Receptor Binding Protein Binding	Protein Binding Toll-like Receptor Binding
	Biological Process	Regulation Of Cytokine Production Positive Regulation Of Cytokine Production T Cell Costimulation Positive Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway	Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways			Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE
Drugs
Diseases
GWAS		Regular attendance at a religious group ( 29970889)	Schizophrenia x sex interaction ( 34099189) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		14 interacting genes: AQP9 BRICD5 BTNL8 C3orf52 ERMP1 FAM3C NIPAL4 NRM PGA4 RPRM SMCO4 TMEM140 TNMD UNC93B1	27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237
Entrez ID		11148	81622
HPRD ID		05082	12191
Ensembl ID		ENSG00000114455	ENSG00000110057
Uniprot IDs		C9J7D0 Q9UM44	Q9H1C4
PDB IDs			7C76 7CYN
Enriched GO Terms of Interacting Partners?
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