KIF3A and RPGR

Number of citations of the paper that reports this interaction (PubMedID 16043481)
69

Data Source:
HPRD (in vivo)

		KIF3A	RPGR
Description		kinesin family member 3A	retinitis pigmentosa GTPase regulator
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Kinesin Complex Microtubule Spindle Microtubule Cilium Microtubule Cytoskeleton Kinesin II Complex Extracellular Exosome Ciliary Tip Axon Cytoplasm	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity Protein Phosphatase Binding Spectrin Binding Small GTPase Binding	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Organelle Organization Microtubule-based Movement Anterograde Axonal Transport Centriole-centriole Cohesion Protein Transport Microtubule Anchoring At Centrosome Cilium Assembly Plus-end-directed Vesicle Transport Along Microtubule Protein Localization To Cell Junction	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Hedgehog 'off' state Intraflagellar transport Activation of SMO Activation of SMO COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31959851 31619474) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23042114 25574825 22197932 26482879) Atopic march ( 26542096) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mosquito bite size ( 28199695) Refractive error ( 32231278)
Interacting Genes		15 interacting genes: APP DISC1 GRB2 KIF3B KIF3C LIG4 MAP3K10 MAP3K11 NEK1 PLEKHA5 PPP1R15A RPGR TRIM14 TULP3 VHL	19 interacting genes: ATP6AP2 DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 NUDT12 PDE6D RPGRIP1 SLC25A10 SLC9A7 SMC1A SMC3 TSPAN7 TUBG1 USP9X YWHAE
Entrez ID		11127	6103
HPRD ID		05250	02425
Ensembl ID		ENSG00000131437	ENSG00000156313
Uniprot IDs		B4DHG8 E9PES4 J3KPF9 Q05CT3 Q9Y496	Q92834
PDB IDs			4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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