UNG and PRDM4

		UNG	PRDM4
Description		uracil DNA glycosylase	PR/SET domain 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Nucleus Cytoplasm Histone Methyltransferase Complex
	Molecular Function	Damaged DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Ribosomal Small Subunit Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Methyltransferase Activity Metal Ion Binding Histone Methyltransferase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA Repair Base-excision Repair Somatic Hypermutation Of Immunoglobulin Genes Negative Regulation Of Apoptotic Process Depyrimidination Isotype Switching Base-excision Repair, AP Site Formation Via Deaminated Base Removal	Transcription By RNA Polymerase II Regulation Of Gene Expression Histone H4-R3 Methylation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			p75NTR negatively regulates cell cycle via SC1
Drugs		4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE 3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid
Diseases
GWAS		Feeling miserable ( 29500382) Feeling worry ( 29500382) Neurociticism ( 29500382) Worry too long after an embarrassing experience ( 29500382)	Acne (severe) ( 24927181) Daytime nap ( 33568662) Sleep duration ( 30846698)
Interacting Genes		15 interacting genes: APP ATP2A2 CAPN11 CCDC33 CRY1 DAO FTH1 KERA P2RY6 PCNA PRDM4 RPA2 RPS20 SEZ6L2 SLC17A7	9 interacting genes: CTNNBL1 DAO EIF4E EMX1 MSRB3 NCS1 SERTAD1 SMAD3 UNG
Entrez ID		7374	11108
HPRD ID		01881	10425
Ensembl ID		ENSG00000076248	ENSG00000110851
Uniprot IDs		E5KTA5 E5KTA6 P13051	A0A024RBM7 B3KPI0 Q9UKN5
PDB IDs		1AKZ 1DPU 1EMH 1EMJ 1Q3F 1SSP 1UGH 1YUO 2HXM 2OXM 2OYT 2SSP 3FCF 3FCI 3FCK 3FCL 3TKB 4SKN 5AYR 5JK7 6VBA	2L9Z 3DB5
Enriched GO Terms of Interacting Partners?
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