ADAP1 and SUPV3L1

Number of citations of the paper that reports this interaction (PubMedID 16176273)
14

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		ADAP1	SUPV3L1
Description		ArfGAP with dual PH domains 1	Suv3 like RNA helicase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Mitochondrial Degradosome
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding	DNA Binding DNA Helicase Activity RNA Binding RNA Helicase Activity Double-stranded RNA Binding Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity 3'-5' RNA Helicase Activity Protein Homodimerization Activity
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Mitochondrial MRNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Mitochondrial RNA 3'-end Processing DNA Recombination RNA Catabolic Process Positive Regulation Of Cell Growth DNA Duplex Unwinding Mitochondrial NcRNA Surveillance Mitochondrial MRNA Surveillance Negative Regulation Of Apoptotic Process Mitochondrion Morphogenesis Mitochondrial RNA Surveillance
Pathways		Nuclear signaling by ERBB4
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Platelet distribution width ( 32888494)	Facial morphology ( 31763980) Glycemic traits (pregnancy) ( 23903356) Immune reponse to smallpox (secreted IL-1beta) ( 22610502)
Interacting Genes		25 interacting genes: ANP32A AP3B2 CSNK1A1 DNAAF5 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PLEKHF2 PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	3 interacting genes: ADAP1 LZTS2 MAGEB6
Entrez ID		11033	6832
HPRD ID		09733	05493
Ensembl ID		ENSG00000105963	ENSG00000156502
Uniprot IDs		A8K3A2 B4DUZ7 O75689	B7Z611 Q8IYB8
PDB IDs		3FEH 3FM8 3LJU 3MDB	3RC3 3RC8
Enriched GO Terms of Interacting Partners?
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