ADAP1 and SF3A3

Number of citations of the paper that reports this interaction (PubMedID 12565890)
4

Data Source:
HPRD (in vitro)

		ADAP1	SF3A3
Description		ArfGAP with dual PH domains 1	splicing factor 3a subunit 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly
Pathways		Nuclear signaling by ERBB4	mRNA Splicing - Major Pathway
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Platelet distribution width ( 32888494)	Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418)
Interacting Genes		25 interacting genes: ANP32A AP3B2 CSNK1A1 DNAAF5 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PLEKHF2 PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	39 interacting genes: ADAP1 APBB1 APP CCDC85B HSPB1 MIR106B MIR107 MIR141 MIR145 MIR155 MIR199A1 MIR200A MIR200C MIR206 MIR214 MIR221 MIR34A MIR34B MIR429 MIR451A MIR7-1 MIRLET7A2 MIRLET7E MIRLET7G MIRLET7I MTNR1B OGT PRMT5 PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212
Entrez ID		11033	10946
HPRD ID		09733	10411
Ensembl ID		ENSG00000105963	ENSG00000183431
Uniprot IDs		A8K3A2 B4DUZ7 O75689	B4DW90 Q12874
PDB IDs		3FEH 3FM8 3LJU 3MDB	2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9 6Y50 6Y53 6Y5Q 7ABG 7ABH 7ABI
Enriched GO Terms of Interacting Partners?
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