NUP50 and KPNA5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NUP50	KPNA5
Description		nucleoporin 50	karyopherin subunit alpha 5
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GO Annotations	Cellular Component	Nuclear Pore Nucleoplasm Nuclear Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Import Into Nucleus MRNA Transport	NLS-bearing Protein Import Into Nucleus
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)	Early cardiac repolarization ( 31600170) Telomere length ( 21460395)
Interacting Genes		14 interacting genes: APP CDKN1B IPO13 KEAP1 KPNA1 KPNA2 KPNA4 KPNA5 KPNA6 KPNB1 OGT RAN SRPK2 XPO1	28 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B DCPS EPAS1 FAM214B FBXO7 HIF1A HNRNPC IL32 KAT5 LMNB1 MLH1 NMNAT1 NRF1 NUP50 POLR3C POU6F2 RAD52 RBBP4 SPOP SPOPL TSEN54 TWIST1 WT1 ZNF326
Entrez ID		10762	3841
HPRD ID		05226	05179
Ensembl ID		ENSG00000093000	ENSG00000196911
Uniprot IDs		A0A024R4X7 B4E2D3 Q9UKX7	O15131
PDB IDs		2EC1 3TJ3	4U2X
Enriched GO Terms of Interacting Partners?
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