LYPLA1 and SFMBT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LYPLA1	SFMBT2
Description		lysophospholipase 1	Scm like with four mbt domains 2
Image
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Nuclear Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytosol Aggresome Nuclear Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Phospholipase Activity Lysophospholipase Activity Protein Binding Palmitoyl-(protein) Hydrolase Activity Lipase Activity Carboxylic Ester Hydrolase Activity	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding
	Biological Process	Protein Depalmitoylation Fatty Acid Metabolic Process Negative Regulation Of Golgi To Plasma Membrane Protein Transport	Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated
Pathways		eNOS activation RAS processing
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Pelvic organ prolapse (moderate/severe) ( 26545240) Urinary albumin-to-creatinine ratio ( 26631737) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)	Asthma (childhood onset) ( 31036433) Fasting blood insulin (BMI interaction) ( 22581228) Femoral neck bone mineral density ( 32239398) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Monoclonal gammopathy of undetermined significance ( 30737484)
Interacting Genes		5 interacting genes: ANXA2 GOLGA2 PIK3CA PLOD2 SFMBT2	11 interacting genes: CLK1 L3MBTL3 LYPLA1 PHC1 SCMH1 SCML1 SCML2 SIAH1 SLF2 TFAP4 UBE2O
Entrez ID		10434	57713
HPRD ID		07063	18853
Ensembl ID		ENSG00000120992	ENSG00000198879
Uniprot IDs		A0A087X1K9 B4DP64 O75608 Q6IAQ1	Q5VUG0
PDB IDs		1FJ2 5SYM 6QGN 6QGO 6QGQ 6QGS	1WJR
Enriched GO Terms of Interacting Partners?
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