UBAC1 and MGAT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UBAC1	MGAT3
Description		UBA domain containing 1	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome	Golgi Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase Activity Protein Binding Glycosyltransferase Activity
	Biological Process	Protein Ubiquitination	N-acetylglucosamine Metabolic Process Protein N-linked Glycosylation Protein Localization Regulation Of Cell Migration Cellular Response To Oxidative Stress Amyloid-beta Metabolic Process Cognition Positive Regulation Of Protein Localization To Early Endosome Negative Regulation Of Lysosomal Protein Catabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Reactions specific to the hybrid N-glycan synthesis pathway
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma (survival time) in never smokers ( 32699080) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)	General cognitive ability ( 29844566) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392 32128391) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Post bronchodilator FEV1 ( 26634245) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 29483656) Sleep duration (short sleep) ( 30846698)
Interacting Genes		36 interacting genes: AIRE APP ARRDC3 CARD14 CCDC138 CDKN1B CPSF6 CSNK2A1 DAZAP2 DVL2 FAM168A HOXA2 HTT IGFBP6 LAPTM5 MAP3K1 MCM10 MGAT3 NEDD4L PLAAT2 PLEKHB2 PMPCA POU6F2 PPP1CB RNF11 RNF123 RNF216 SMURF1 SPART TRIM2 TRIM39 UBB UBC UBQLN2 ZDHHC17 ZG16B	2 interacting genes: HSPD1 UBAC1
Entrez ID		10422	4248
HPRD ID		12170	07058
Ensembl ID		ENSG00000130560	ENSG00000128268
Uniprot IDs		A0A140VK64 Q9BSL1	Q09327
PDB IDs		2DAI
Enriched GO Terms of Interacting Partners?
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