SPRY3 and ZNF655

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPRY3	ZNF655
Description		sprouty RTK signaling antagonist 3	zinc finger protein 655
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Nucleus Nucleolus Cytoplasm
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Molecular_function Protein Binding Metal Ion Binding
	Biological Process	Multicellular Organism Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of MAPK Cascade Negative Regulation Of Ras Protein Signal Transduction Animal Organ Development Axon Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neuron Projection Arborization	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Idiopathic osteonecrosis of the femoral head ( 28000841) Iron status biomarkers (transferrin saturation) ( 28334935)	Serum metabolite levels ( 23093944)
Interacting Genes		27 interacting genes: AQP1 BEX2 CATSPER1 CHRD CREB5 GNE GPSM3 HOXA1 HR KPRP KRT34 LCE1A LCE1B LCE1F LCE2B LCE3A LCE3D LCE3E MAPKBP1 MEOX2 NEK6 R3HDM2 SLC39A7 VSNL1 ZDHHC17 ZNF587 ZNF655	156 interacting genes: ACSL6 ANKRD11 AP1M1 ASB6 ASMTL ATPAF2 BARD1 BORCS6 BYSL C8orf34 C8orf74 CAPN7 CARD9 CBY2 CCDC116 CCDC179 CCDC57 CCDC74A CCHCR1 CCNH CDC37 CDK4 CDR2L CEP57L1 CPNE7 CRACR2A CWF19L2 DBF4B DEUP1 DPF2 DUSP4 EGLN3 EIF4EBP1 EMILIN1 EVL EXOSC5 FADS2 FAM214B FAM81A FAM81B FAM90A1 FARS2 FHL2 FKBP6 GEM GFAP GSTP1 GUCD1 HAPLN2 HEXIM2 HOMER3 HOOK1 HOXB5 HPCAL1 HSD3B7 HTT IDI1 IMP3 INTS10 INTS13 IP6K3 ITGB5 JRK KIFC3 KRT40 KRT76 KRT85 KRT86 KRTAP4-12 KRTAP5-9 KRTAP9-8 LCE3C LCE4A LCE5A LGALS14 LMO2 LNX1 LRRC29 MACO1 MAD2L2 MAGEA11 MAGEA2B MBD3 MED21 MEMO1 METTL21A MIS18A MITD1 MPP3 MRFAP1 MRPL28 MTMR9 MTUS2 MXI1 NAA10 NDC80 NECAB2 NGB NOTUM NUDT21 NUDT22 NXT2 OIP5 OSTF1 OTUD4 P2RX7 PABPC4 PBX3 PCSK5 PFKFB1 POLR1C PRR35 RIN3 RINT1 RRM1 RUNX1T1 SH2D4A SIGLEC6 SLC12A4 SMARCD1 SMG9 SPANXN2 SPRED1 SPRY3 SRGAP2B SZT2 TCEANC TEKT4 TEX28 THAP6 TIMM10 TLK1 TNS2 TRAF2 TRAF5 TRAPPC2 TRAPPC2B TRIM37 TRIM41 TRIM72 TRIP13 TSPYL4 TXNDC9 USHBP1 VAV1 VPS26C VPS9D1 XPA YPEL5 ZBTB16 ZC2HC1C ZNF330 ZNF552 ZNF648 ZNF792 ZNF837
Entrez ID		10251	79027
HPRD ID		03917	11673
Ensembl ID		ENSG00000168939	ENSG00000197343
Uniprot IDs		O43610 Q6ZUP3	Q68DU4 Q8N720
PDB IDs
Enriched GO Terms of Interacting Partners?
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