MBNL2 and SNRPA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MBNL2	SNRPA
Description		muscleblind like splicing regulator 2	small nuclear ribonucleoprotein polypeptide A
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleoplasm Spliceosomal Complex U1 SnRNP
	Molecular Function	RNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding U1 SnRNA Binding Identical Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of RNA Splicing	MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs			Malonic acid
Diseases
GWAS		Alcoholism (alcohol dependence factor score) ( 21529783) Alcoholism (alcohol use disorder factor score) ( 21529783) Diastolic blood pressure ( 30224653) Energy expenditure (24h) ( 28476931) Lung function in heavy smokers (high FEV1 vs average FEV1) ( 26423011) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Platelet reactivity in response to clopidogrel treatment ( 32472697) Pre-treatment viral load in HIV-1 infection ( 31219150)	Blood protein levels ( 28240269) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Hematocrit ( 27863252) melanoma-derived growth regulatory protein levels ( 25147954) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		2 interacting genes: SNRPA TIAL1	54 interacting genes: CDKN2A CHTOP CIRBP DAPK1 DAZAP1 DDIT4L DDX39B ENOX2 EP300 FBXO7 FUBP1 GABPB1 GIGYF1 HNRNPK IL7R LENG8 LHX4 LNX1 MBNL2 METTL13 MRPL15 MTUS2 NDUFAF3 OTX2 PAPOLA PCBP1 PCBP2 PCBP3 PTBP1 PTBP2 QKI RASAL3 RBM11 RBM3 RBM42 RBM4B RBMX RBMY1A1 RBMY1F RBMY1J RBPMS2 SDCBP SFPQ SMAD5 SNRPA1 TIAL1 TLE5 TNFAIP8L1 TRIM27 TRIR U2AF2 UBC WBP4 ZCCHC13
Entrez ID		10150	6626
HPRD ID		09543	01658
Ensembl ID		ENSG00000139793	ENSG00000077312
Uniprot IDs		A2A3S3 Q5VZF2	P09012
PDB IDs		2E5S 2RPP	1AUD 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 3UTR 4C4W 4PR6 4PRF 4W90 4W92 4YB1 5DDO 5DDP 5DDQ 5DDR 5FJ4 6LAS 6LAU 6LAX 6LAZ 6QX9 6SQN 6SQQ 6SQT 6SQV 6SR7 6XH0 6XH1 6XH2 6XH3 7AEP 7B0Y 7D7V
Enriched GO Terms of Interacting Partners?
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