ACTR3 and ZMYND10

		ACTR3	ZMYND10
Description		actin related protein 3	zinc finger MYND-type containing 10
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Arp2/3 Protein Complex Brush Border Cell-cell Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Site Of Double-strand Break Extracellular Exosome	Cytoplasm Apical Plasma Membrane Centriolar Satellite Dynein Axonemal Particle
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Actin Filament Binding	Protein Binding Protein Folding Chaperone Metal Ion Binding Molecular Adaptor Activity
	Biological Process	Establishment Or Maintenance Of Cell Polarity Asymmetric Cell Division Positive Regulation Of Lamellipodium Assembly Meiotic Chromosome Movement Towards Spindle Pole Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Transcription By RNA Polymerase II Spindle Localization Cilium Assembly Actin Polymerization-dependent Cell Motility Cellular Response To Interferon-gamma	Cilium Movement Protein Folding Outer Dynein Arm Assembly Inner Dynein Arm Assembly Motile Cilium Assembly Protein Localization To Cilium Positive Regulation Of Motile Cilium Assembly
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs		N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Body shape index ( 34021172) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Systolic blood pressure in sickle cell anemia ( 24058526) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		19 interacting genes: ACTR2 ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CDH1 CTTN ERCC6 HCLS1 JUND LINC01554 OGT SHARPIN UBE3A WASF2 WASF3 WASL ZMYND10	20 interacting genes: ACTR3 CDR1 CLK1 CYSRT1 EIF3M IFT43 KRTAP10-3 MTUS2 NR0B2 NUTM1 NUTM2F RALGDS RBM11 RNF181 SERINC1 SNX11 TBX5 TCF4 TSC22D4 WBP1
Entrez ID		10096	51364
HPRD ID		05024	06145
Ensembl ID		ENSG00000115091	ENSG00000004838
Uniprot IDs		A0A024RAI1 B4DXW1 P61158	O75800
PDB IDs		6UHC 6YW6 6YW7	2D8Q 2DAN
Enriched GO Terms of Interacting Partners?
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