ZMYND10 and TBX5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZMYND10	TBX5
Description		zinc finger MYND-type containing 10	T-box transcription factor 5
Image
GO Annotations	Cellular Component	Cytoplasm Apical Plasma Membrane Centriolar Satellite Dynein Axonemal Particle	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex Protein-DNA Complex
	Molecular Function	Protein Binding Protein Folding Chaperone Metal Ion Binding Molecular Adaptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding DNA-binding Transcription Factor Binding
	Biological Process	Cilium Movement Protein Folding Outer Dynein Arm Assembly Inner Dynein Arm Assembly Motile Cilium Assembly Protein Localization To Cilium Positive Regulation Of Motile Cilium Assembly	Cell Fate Specification Morphogenesis Of An Epithelium Bundle Of His Development Atrioventricular Bundle Cell Differentiation Atrioventricular Valve Morphogenesis Endocardial Cushion Development Cardiac Left Ventricle Formation Ventricular Septum Development Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Pattern Specification Process Heart Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Epithelial To Mesenchymal Transition Lung Development Embryonic Limb Morphogenesis Negative Regulation Of Cell Migration Embryonic Forelimb Morphogenesis Forelimb Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cardioblast Differentiation Pericardium Development Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Atrial Septum Morphogenesis Atrioventricular Node Cell Development Atrioventricular Node Cell Fate Commitment Cell Migration Involved In Coronary Vasculogenesis Positive Regulation Of Secondary Heart Field Cardioblast Proliferation Cell-cell Signaling Involved In Cardiac Conduction Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Gap Junction Assembly Positive Regulation Of Cardiac Conduction
Pathways			YAP1- and WWTR1 (TAZ)-stimulated gene expression Physiological factors
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Airflow obstruction ( 22837378) Atrial fibrillation ( 28416818 28416822 30061737 29892015) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Blood pressure ( 21909110) Bone mineral density (total hip) ( 29883787) Diastolic blood pressure ( 28135244 19430479 27618452) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diverticular disease ( 30177863) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 20062063) Electrocardiographic traits (multivariate) ( 32602732) FEV1 ( 30804560) Hypertension ( 30487518) Laryngeal squamous cell carcinoma ( 25194280) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lung function in heavy smokers (low FEV1 vs high FEV1) ( 26423011) Mean arterial pressure ( 30487518) Obesity-related traits ( 23251661) P wave duration ( 28794112) Peak expiratory flow ( 30804560) Pelvic organ prolapse ( 32184442) Percent mammographic density ( 22532574) PR interval ( 30046033 32439900 20062060 25035420 23139255 21347284) Prostate cancer ( 23535732 25939597) QRS duration ( 27577874 30012220 21076409) Receptive language ability ( 32635940) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 27618452) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Visceral fat ( 22589738)
Interacting Genes		20 interacting genes: ACTR3 CDR1 CLK1 CYSRT1 EIF3M IFT43 KRTAP10-3 MTUS2 NR0B2 NUTM1 NUTM2F RALGDS RBM11 RNF181 SERINC1 SNX11 TBX5 TCF4 TSC22D4 WBP1	7 interacting genes: BAIAP2 FBXO25 GATA4 KAT5 KDM6A NKX2-5 ZMYND10
Entrez ID		51364	6910
HPRD ID		06145	03372
Ensembl ID		ENSG00000004838	ENSG00000089225
Uniprot IDs		O75800	Q99593
PDB IDs		2D8Q 2DAN	2X6U 2X6V 4S0H 5BQD
Enriched GO Terms of Interacting Partners?
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