AP1M2 and AP1S1

Number of citations of the paper that reports this interaction (PubMedID 10535737)
192

Data Source:
HPRD (in vivo)

		AP1M2	AP1S1
Description		adaptor related protein complex 1 subunit mu 2	adaptor related protein complex 1 subunit sigma 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin-coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Clathrin Adaptor Activity	Clathrin Adaptor Activity
	Biological Process	Protein Targeting Vesicle Targeting Vesicle-mediated Transport	Intracellular Protein Transport Receptor-mediated Endocytosis Response To Virus Vesicle-mediated Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414)	Adult body size ( 32376654) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		21 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH CDK12 ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2	7 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 PICK1 RHOU TNFRSF9
Entrez ID		10053	1174
HPRD ID		06296	04635
Ensembl ID		ENSG00000129354	ENSG00000106367
Uniprot IDs		Q53GI5 Q9Y6Q5	A0A024QYT6 P61966
PDB IDs			4P6Z
Enriched GO Terms of Interacting Partners?
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