NR2E3 and ELAVL2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		NR2E3	ELAVL2
Description		nuclear receptor subfamily 2 group E member 3	ELAV like RNA binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex	Nucleoplasm Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Signal Transduction Visual Perception Phototransduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cell Differentiation Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Retina Development In Camera-type Eye	Regulation Of Transcription, DNA-templated
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Macular thickness ( 30535121) Metabolite levels (HVA/MHPG ratio) ( 23319000) Red blood cell count ( 32888494)	Anxiety ( 33859377) Asthma ( 30929738 34103634) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Attending social / leisure activities ( 34054130) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Chronic obstructive pulmonary disease ( 30804561) Feeling guilty ( 29500382) Fulminant type 1 diabetes ( 30552108) General cognitive ability ( 29844566) Glomerular filtration rate change in heart transplantation ( 30160337) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Lung function (FEV1/FVC) ( 30061609) Neurociticism ( 29500382) Neuroticism ( 27089181 29255261 27067015) Physiological traits ( 31902109) Plasma t-tau levels ( 28100725) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Schizophrenia ( 33169155) Sociability score ( 34054130)
Interacting Genes		29 interacting genes: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 NRL POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 WDR5 ZNF232	10 interacting genes: CDKN2B ELAVL3 ELAVL4 GLIPR2 HNRNPAB HOXC9 IL11RA NR2E3 RBFOX2 SECISBP2
Entrez ID		10002	1993
HPRD ID		05132	03396
Ensembl ID		ENSG00000278570	ENSG00000107105
Uniprot IDs		F1D8Q9 Q9Y5X4	A0A0A0MRX1 Q12926
PDB IDs		4LOG
Enriched GO Terms of Interacting Partners?
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