ELAVL2 and ELAVL4

Number of citations of the paper that reports this interaction (PubMedID 12384599)
28

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		ELAVL2	ELAVL4
Description		ELAV like RNA binding protein 2	ELAV like RNA binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Ribonucleoprotein Complex	Nuclear Envelope Cytoplasm Cytosol Cytoskeleton Membrane Axon Dendrite Growth Cone Polysomal Ribosome Perikaryon Glutamatergic Synapse
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding	MRNA 3'-UTR Binding Poly(A) Binding MRNA 3'-UTR AU-rich Region Binding Translation Regulator Activity Pre-mRNA Intronic Pyrimidine-rich Binding
	Biological Process	Regulation Of Transcription, DNA-templated	RNA Processing MRNA Processing Aging Locomotory Behavior Associative Learning RNA Splicing Cerebral Cortex Neuron Differentiation Regeneration Response To Endoplasmic Reticulum Stress Response To Cocaine Dendrite Morphogenesis 3'-UTR-mediated MRNA Stabilization Regulation Of Translation At Synapse, Modulating Synaptic Transmission Positive Regulation Of Dendrite Development Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Cellular Response To Nerve Growth Factor Stimulus
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Anxiety ( 33859377) Asthma ( 30929738 34103634) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Attending social / leisure activities ( 34054130) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Chronic obstructive pulmonary disease ( 30804561) Feeling guilty ( 29500382) Fulminant type 1 diabetes ( 30552108) General cognitive ability ( 29844566) Glomerular filtration rate change in heart transplantation ( 30160337) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Lung function (FEV1/FVC) ( 30061609) Neurociticism ( 29500382) Neuroticism ( 27089181 29255261 27067015) Physiological traits ( 31902109) Plasma t-tau levels ( 28100725) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Schizophrenia ( 33169155) Sociability score ( 34054130)	Alcohol consumption ( 31358974) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 26961502 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Male-pattern baldness ( 28196072) Obesity-related traits ( 23251661) Schizophrenia ( 30285260) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077)
Interacting Genes		10 interacting genes: CDKN2B ELAVL3 ELAVL4 GLIPR2 HNRNPAB HOXC9 IL11RA NR2E3 RBFOX2 SECISBP2	6 interacting genes: ELAVL2 EWSR1 GAP43 NFX1 NXF1 PHF20L1
Entrez ID		1993	1996
HPRD ID		03396	01343
Ensembl ID		ENSG00000107105	ENSG00000162374
Uniprot IDs		A0A0A0MRX1 Q12926	A0A0R4J2E6 A0A494C0F8 A0A494C0M6 A0A494C147 B1APY9 P26378
PDB IDs			1FXL 1G2E
Enriched GO Terms of Interacting Partners?
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