RNF34 and PHF7

Data Source:
BioGRID (two hybrid)

		RNF34	PHF7
Description		ring finger protein 34	PHD finger protein 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Endomembrane System Nuclear Body Nuclear Speck	Nucleus Nucleoplasm Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck
	Molecular Function	P53 Binding Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity Phosphatidylinositol Phosphate Binding	Protein Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Protein Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Oxygen Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Pathways		Regulation of TP53 Degradation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872) Triglyceride levels ( 32154731)
Interacting Genes		10 interacting genes: APP APPBP2 DNAJA3 MAVS NOD1 PHF7 TRIM23 UBE2D2 UBE2F UBE2H	18 interacting genes: APP ARIH2 DTX3L FBXL17 H3-4 IKBKG MAGEF1 MDM2 RNF111 RNF14 RNF34 SRPK1 TRIM26 TRIM41 UBE2D2 UBE2D4 USP1 USP15
Entrez ID		80196	51533
HPRD ID		10509	15127
Ensembl ID		ENSG00000170633	ENSG00000010318
Uniprot IDs		A0A087WTM5 Q969K3	A0A024R336 A8K856 Q9BWX1
PDB IDs
Enriched GO Terms of Interacting Partners?
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