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LAPTM5 and MRPL18
Data Source:
BioGRID
(two hybrid)
LAPTM5
MRPL18
Description
lysosomal protein transmembrane 5
mitochondrial ribosomal protein L18
Image
No pdb structure
GO Annotations
Cellular Component
Lysosome
Lysosomal Membrane
Cytosol
Integral Component Of Plasma Membrane
Transport Vesicle
Cytoplasmic Vesicle
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Extracellular Space
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Ribosome
Mitochondrial Large Ribosomal Subunit
Molecular Function
Protein Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-dependent Protein Binding
Protein Sequestering Activity
Structural Constituent Of Ribosome
Protein Binding
5S RRNA Binding
Biological Process
Defense Response To Tumor Cell
Positive Regulation Of Cytokine Production Involved In Immune Response
Protein Targeting To Lysosome
Intracellular Protein Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Induction Of Programmed Cell Death
Positive Regulation Of Protein Ubiquitination
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of MAPK Cascade
Negative Regulation Of T Cell Receptor Signaling Pathway
Negative Regulation Of T Cell Activation
Negative Regulation Of B Cell Activation
Positive Regulation Of Macrophage Cytokine Production
Golgi To Lysosome Transport
Positive Regulation Of Lysosomal Membrane Permeability
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Autophagic Cell Death
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Receptor Catabolic Process
Translation
RRNA Import Into Mitochondrion
Mitochondrial Translational Elongation
Mitochondrial Translational Termination
Pathways
Mitochondrial translation initiation
Mitochondrial translation elongation
Mitochondrial translation elongation
Mitochondrial translation termination
Drugs
Diseases
GWAS
Loneliness (
27629369
)
Loneliness (linear analysis) (
27629369
)
Neutrophil count (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
39 interacting genes:
AIG1
ANKRD13A
C4orf3
CLDN19
CYB5R3
DCUN1D1
DISP1
EPN1
EPN2
EPN3
EPS15
GYPA
HERC1
HEY1
HEYL
HMOX2
HUWE1
INSIG2
ITCH
KIR3DL3
KRT7
LDLRAD1
MRPL18
NEDD4
NEDD4L
RNF168
RPRM
RTP2
SLC22A2
SMURF2
TNFAIP3
TOM1L2
UBA52
UBAC1
UBC
UBE2J1
USP13
VAMP1
WWP1
2 interacting genes:
LAPTM5
MRPL38
Entrez ID
7805
29074
HPRD ID
03280
14744
Ensembl ID
ENSG00000162511
ENSG00000112110
Uniprot IDs
Q13571
Q5TBB8
Q9H0U6
PDB IDs
3J7Y
5OOL
5OOM
6NU2
6NU3
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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