PFN2 and IVNS1ABP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PFN2	IVNS1ABP
Description		profilin 2	influenza virus NS1A binding protein
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Extracellular Exosome	Nucleoplasm Transcription Regulator Complex Spliceosomal Complex Cytosol Cytoskeleton
	Molecular Function	Actin Binding Actin Monomer Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding ATPase Activity	Protein Binding
	Biological Process	Negative Regulation Of Epithelial Cell Migration Actin Cytoskeleton Organization Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of ATPase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Protein Stabilization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly	Transcription By RNA Polymerase III RNA Splicing Response To Virus Viral Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Signaling by ROBO receptors RHO GTPases Activate Formins RHO GTPases Activate Formins
Drugs		Triglyme Pentaglyme
Diseases
GWAS		Fish- and plant-related diet ( 32066663)	Lead levels ( 26025379)
Interacting Genes		34 interacting genes: ACTB ACTG1 ANTKMT BIRC2 CCDC113 DDX11 DLST DNM1 EEF1A1 ERCC6 EVL FHOD1 FLT3LG FMNL1 GOLGB1 HTT IK IVNS1ABP MSANTD3 MYPOP NDUFB8 PLAUR PTPRS RAP1GAP RNF146 ROCK1 RPS10 SEPTIN5 SGTA SNTA1 SYN1 TERF1 VASP WDR33	11 interacting genes: AHR CHD3 ENO1 KLHL20 PFN2 POLR1H RPL6 SYNCRIP TRA2B TRIM14 VIM
Entrez ID		5217	10625
HPRD ID		01451	10004
Ensembl ID		ENSG00000070087	ENSG00000116679
Uniprot IDs		P35080	Q9Y6Y0
PDB IDs		1D1J	5YY8 6N34 6N3H
Enriched GO Terms of Interacting Partners?
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