ARFIP2 and DGAT2L6

Data Source:
BioGRID (two hybrid)

		ARFIP2	DGAT2L6
Description		ADP ribosylation factor interacting protein 2	diacylglycerol O-acyltransferase 2 like 6
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Plasma Membrane Cell Cortex Trans-Golgi Network Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity	Protein Binding O-acyltransferase Activity
	Biological Process	Intracellular Protein Transport Autophagy Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Lipid Metabolic Process Monoacylglycerol Biosynthetic Process Acylglycerol Acyl-chain Remodeling
Pathways		Retrograde transport at the Trans-Golgi-Network	Acyl chain remodeling of DAG and TAG
Drugs
Diseases
GWAS		Malaria ( 31844061)
Interacting Genes		61 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARFIP1 ARL1 BLOC1S2 C19orf25 CDKN2A CDR1 CEP63 CMTM5 CYTH3 DGAT2L6 DMAP1 DTNBP1 FADS6 FSD2 GOLGA2 GSG1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 KRT16 LNX1 LY6D MAL2 MIEF1 MIEF2 NDRG4 NRDE2 NUP62 PBX3 PKNOX2 PLP2 PPIF RAC1 RAC2 RAC3 REEP5 REL RND1 SCAMP1 SCAMP5 SDCBP SH3GLB1 SMG9 SNX1 SOCS2 STAT3 SYP TMEM255B TRIM54 TTPA USHBP1	45 interacting genes: ABHD4 ABHD5 ACSF2 AQP6 ARFIP2 BNIP2 CIAO2A DIABLO ECPAS FARS2 FBXL19 FCER1G GAD2 GPR152 HSD17B11 MCEMP1 MPP1 MTERF4 MYG1 NAPB NDRG4 PBX3 PGRMC2 PITPNC1 REEP4 RNF144A RNF5 RUSF1 SCAND1 SCN3B SLC10A1 SLC10A6 SMG9 SNX4 STAR THAP4 TMED8 TMEM143 TMEM14B TMEM255B TMEM31 TMX2 TTPA TUFM WIPI2
Entrez ID		23647	347516
HPRD ID		07209	13141
Ensembl ID		ENSG00000132254	ENSG00000184210
Uniprot IDs		A0A087X1E4 B4DUZ3 B4DXH2 P53365	Q6ZPD8
PDB IDs		1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?
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