ARFIP2 and C19orf25

Data Source:
BioGRID (two hybrid)

		ARFIP2	C19orf25
Description		ADP ribosylation factor interacting protein 2	chromosome 19 open reading frame 25
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Plasma Membrane Cell Cortex Trans-Golgi Network Membrane
	Molecular Function	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity	Protein Binding
	Biological Process	Intracellular Protein Transport Autophagy Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Malaria ( 31844061)	Lean body mass ( 28552196) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		61 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARFIP1 ARL1 BLOC1S2 C19orf25 CDKN2A CDR1 CEP63 CMTM5 CYTH3 DGAT2L6 DMAP1 DTNBP1 FADS6 FSD2 GOLGA2 GSG1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 KRT16 LNX1 LY6D MAL2 MIEF1 MIEF2 NDRG4 NRDE2 NUP62 PBX3 PKNOX2 PLP2 PPIF RAC1 RAC2 RAC3 REEP5 REL RND1 SCAMP1 SCAMP5 SDCBP SH3GLB1 SMG9 SNX1 SOCS2 STAT3 SYP TMEM255B TRIM54 TTPA USHBP1	20 interacting genes: ARFIP2 BAIAP2 BORCS6 BRME1 CCDC153 CCDC85B CEP170P1 CRX DDIT4L EPS8 INSYN1 KRT75 KRTAP1-3 KRTAP10-8 MEI4 NECAB2 PNMA3 RINT1 SAT1 TFPT
Entrez ID		23647	148223
HPRD ID		07209	12703
Ensembl ID		ENSG00000132254	ENSG00000119559
Uniprot IDs		A0A087X1E4 B4DUZ3 B4DXH2 P53365	Q9UFG5
PDB IDs		1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?
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