ATF2 and CCDC6

Number of citations of the paper that reports this interaction (PubMedID 20498639)
16

Data Source:
BioGRID (pull down)

		ATF2	CCDC6
Description		activating transcription factor 2	coiled-coil domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Site Of Double-strand Break	Cytosol Cytoskeleton
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding CAMP Response Element Binding Protein Binding Protein Kinase Binding CAMP Response Element Binding Protein-containing Complex Binding Metal Ion Binding	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Outflow Tract Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Cellular Response To DNA Damage Stimulus Response To Water Deprivation Positive Regulation Of Gene Expression Negative Regulation Of Angiogenesis Histone Acetylation Intra-S DNA Damage Checkpoint Positive Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Neuron Apoptotic Process Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epithelial Cell Proliferation Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of DNA-binding Transcription Factor Activity Adipose Tissue Development Amelogenesis Positive Regulation Of Cardiac Muscle Myoblast Proliferation Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process	Cytoskeleton Organization Biological_process
Pathways		Transcriptional activation of mitochondrial biogenesis HATs acetylate histones Circadian Clock Activation of the AP-1 family of transcription factors TP53 Regulates Transcription of DNA Repair Genes Regulation of PTEN gene transcription Regulation of PTEN gene transcription Estrogen-dependent gene expression NGF-stimulated transcription NGF-stimulated transcription Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK4 (GCN2) to amino acid deficiency
Drugs		Pseudoephedrine
Diseases			Thyroid cancer
GWAS		Intake of total sugars ( 31005972) Metabolite levels ( 23823483)	Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		55 interacting genes: APP AR ATF3 ATF4 ATF7 BACH1 BATF CCDC6 CCND1 CEBPA CEBPB CEBPG CREB5 CSNK2A1 CSNK2A2 DDIT3 DNMT3L EDF1 ETS1 EXOSC8 FOS FOSL1 GTF2F2 H2BC21 HMGA1 IRF2BP1 JDP2 JUN KIFC3 MACROH2A1 MAPK1 MAPK10 MAPK11 MAPK13 MAPK14 MAPK8 MAPK9 MAPKAPK5 MLH1 NBN NCOA6 PML PRKCE RB1 RPS6KA5 RUVBL2 SMAD3 SMAD4 SRA1 SUMO1 THRB UBE2I UTF1 XPO1 YY1	7 interacting genes: ATF2 CREB1 CSNK2A1 FBXW7 MAPK3 PPP4C UBE2I
Entrez ID		1386	8030
HPRD ID		00443	09064
Ensembl ID		ENSG00000115966	ENSG00000108091
Uniprot IDs		A4D7V5 P15336	Q05CP8 Q16204
PDB IDs		1BHI 1T2K 4H36
Enriched GO Terms of Interacting Partners?
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