POM121 and TRIP6

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POM121	TRIP6
Gene Name		POM121 transmembrane nucleoporin	thyroid hormone receptor interactor 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Membrane Nuclear Membrane	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Interleukin-1 Receptor Complex
	Molecular Function		Interleukin-1 Receptor Binding Protein Binding Zinc Ion Binding Kinase Binding Poly(A) RNA Binding Thyroid Hormone Receptor Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Release Of Cytoplasmic Sequestered NF-kappaB Positive Regulation Of Cell Migration Focal Adhesion Assembly
Pathways		Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738)	Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
Protein-Protein Interactions		21 interactors: AGR2 AP2B1 APC ATXN1 BRCA1 CEP55 CEP76 CLDN3 COL4A3BP FXR2 GFAP GOLGA2 GYG1 HOMER3 LPXN NFKBIA PAXIP1 RBPMS TEX11 TRIM23 TRIP6	105 interactors: ABI2 ADAMTSL4 AQP1 ARNT2 ATN1 ATP5O ATXN1 BCAR1 BYSL CATSPER1 CBLC CCL5 CEP57L1 CNTF CREB5 CTAG2 DHX37 DMRT3 DTX2 EXOC3-AS1 FAM124B FAM154A FAM46C FASLG FHL3 FRS3 GDPD5 GFI1B GNAI2 GSE1 HLA-DPB1 HOXA1 HOXA9 HOXB9 HYKK ILF3 INCA1 KIAA1683 KIF1A KIR2DL4 KLK15 KRTAP26-1 LMO2 LOC149950 LPAR2 MAPKBP1 MEMO1 METTL17 MSRB3 MVP NCK2 NEDD9 NEU4 NUP210 ODF1 OIP5 OTUB2 PDGFRB PDLIM4 PIN1 POM121 POM121L4P PPP1R16A PRKAA1 PRKAA2 PTK2 PTPN13 PXN RAD23A RERE RFX3 RHOA RHOQ RNF213 RNF214 SCRIB SIK3 SLC15A3 SLC25A6 SMAD1 SON SRC STAC STK16 SVIL SYNGAP1 TAB1 TCAF1 TEKT4 THRB TLR2 TMSB4X TPM3 TPM4 TRAF3IP2 TRAPPC2L TRIM29 TTLL10 TXN2 TXNDC5 VCL WT1-AS XRCC6BP1 YPEL3 ZBP1
Entrez ID		9883	7205
HPRD ID		11448	04242
Ensembl ID		ENSG00000196313	ENSG00000087077
Uniprot IDs		Q96HA1	F2ZC06 Q15654
PDB IDs			1X61 2DLO
Enriched GO Terms of Interacting Partners?		Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Negative Regulation Of Signal Transduction Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Signaling Regulation Of Microtubule-based Process Regulation Of Protein Import Into Nucleus Positive Regulation Of Histone Methylation Mitotic Cytokinesis Regulation Of NF-kappaB Import Into Nucleus Regulation Of Signaling Regulation Of Protein Localization To Nucleus Regulation Of Centrosome Duplication Regulation Of Chromosome Organization Regulation Of Histone Acetylation Cell Cycle Regulation Of Nucleocytoplasmic Transport Regulation Of Centrosome Cycle Signaling Regulation Of Histone Methylation Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Schwann Cell Proliferation Cell Communication DNA Recombination Cellular Response To Stress Regulation Of Intracellular Protein Transport Regulation Of Signal Transduction Cell Cycle Process Positive Regulation Of Histone Modification Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Mucus Secretion Positive Regulation Of Histone H3-K9 Acetylation ER To Golgi Ceramide Transport Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Signal Transduction Response To Abiotic Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Chromosome Organization Lung Goblet Cell Differentiation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Transcription Factor Import Into Nucleus Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Import Into Nucleus	Signal Complex Assembly Cellular Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Response To Organic Substance Regulation Of Signaling Actin Filament-based Process Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Positive Regulation Of Intracellular Signal Transduction Response To Growth Factor Cytoskeleton Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction ERBB Signaling Pathway Cell Communication Cellular Process Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorylation Multicellular Organismal Development Regulation Of Apoptotic Process Response To Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Response To Transforming Growth Factor Beta Regulation Of Protein Phosphorylation Cellular Response To Stimulus Platelet Activation Response To Hormone Response To Stress Cellular Response To Growth Factor Stimulus Response To Wounding Regulation Of Protein Metabolic Process Regulation Of Cell Death Actin Cytoskeleton Organization Wound Healing Signaling Transforming Growth Factor Beta Receptor Signaling Pathway Organ Development Regulation Of Cell Motility Cell Motility Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Process
Tagcloud ?		antagonize brd1 brings childhood chimeric comprise dach1 encoding fluorescence frame fusion fusions hipk1 hybridization identification implicated least leukemia lymphoblastic master occur partner pax5 precursor rearrangements regulator situ transduction tumorigenesis	adaptors ap competition dimerization discrete domains enables enhances example exerts focal glucocorticoid gr interacts intriguing isoform lim med1 mediating mediator negatively orchestrating promoters recruitment tethering thought thrap3 transrepression
Tagcloud (Difference) ?		antagonize brd1 brings childhood chimeric comprise dach1 encoding fluorescence frame fusion fusions hipk1 hybridization identification implicated least leukemia lymphoblastic master occur partner pax5 precursor rearrangements regulator situ transduction tumorigenesis	adaptors ap competition dimerization discrete domains enables enhances example exerts focal glucocorticoid gr interacts intriguing isoform lim med1 mediating mediator negatively orchestrating promoters recruitment tethering thought thrap3 transrepression
Tagcloud (Intersection) ?